Best Korean Ampoule for Acne Scars and Hyperpigmentation: Why Incellderm RADIANSOME100 Outshines Them All
Skincare
November 1, 2025
Written by Joseph Kim

If you’re looking for the best Korean ampoule for acne scars and hyperpigmentation, you’re in the right place. In this blog post I’ll break down what to look for, highlight a few standout Korean ampoules that address post-inflammatory hyperpigmentation (PIH) and acne scars, and explain why I believe the Incellderm ‡ RADIANSOME100 Microfluidizer Ampoule is the top pick for your skin-goal of smoother, more even tone.

Why acne scars & hyperpigmentation need a targeted approach

After a breakout, what remains on the surface of the skin is often not simply a pimple but a mark: either a darker patch of pigment (PIH), a red or pink mark (post-inflammatory erythema, PIE), or even a change in texture (atrophic or raised scars). As one Korean skincare guide explains:

“Post-Inflammatory Hyperpigmentation (PIH): dark spots or discoloration left after a breakout… Atrophic Scars: depressed scars like ice-pick, boxcar, or rolling scars.”
What you want in an ampoule (and skincare in general) for these concerns:

  • Brightening / pigment-inhibiting ingredients (e.g., niacinamide, vitamin C, arbutin, tranexamic acid)
  • Repair and regeneration support (e.g., peptides, snail mucin, centella)
  • Gentle exfoliation or ingredients that help skin turnover (for dark spots) plus ingredients that help rebuild for texture issues.
  • Sun protection and consistency—without protecting from UV, hyperpigmentation lingers.

K-beauty is particularly strong in this field because many ampoules and serums are lightweight, designed for layering, and use highly concentrated technologies. For example, a skincare write-up states:

“Ampoules are typically more concentrated and ‘deliver results slightly faster than serums’…"

With that in mind, let’s look at a few excellent Korean ampoule options before narrowing down to the one I believe leads the pack.

Top Korean Ampoules for Acne Scars & Hyperpigmentation

Here are some excellent options worth considering—each with strong back-stories and ingredient profiles.

1. SKIN1004 Madagascar Centella Ampoule

This lightweight ampoule focuses on the healing side of post-breakout skin. According to StyleCraze’s “best Korean ampoule” list:

“The Madagascar Centella Ampoule … treats various skin concerns like dark spots and dehydrated patches.”
If your skin is acne‐prone and sensitive, dealing with both marks and redness, this is a strong pick.

2. COSRX Propolis Light Ampoule

Also featured by StyleCraze:

“This super-moisturizing serum … is a boon for people with textured, acne-prone, and pigmented skin.”
The propolis extract supports soothing inflammation and calming skin, which helps when you're trying to fade marks from breakouts rather than new ones forming.

3. Beauty of Joseon Glow Deep Serum (not exactly an ampoule, but very relevant)

In a review of Korean skincare for acne scars:

“Which Korean serum is best for dark spots? … The Beauty of Joseon Glow Deep Serum is highly recommended for dark spots.”
It contains niacinamide + rice water + arbutin-type actives—good for hyperpigmentation.

Why I Recommend the RADIANSOME100 Microfluidizer Ampoule as theBest

After reviewing the above and comparing formulas, I believe the Incellderm RADIANSOME100 Microfluidizer Ampoule stands out for several reasons.

• Advanced technology & delivery

The product is described by Incellderm as:

“Our most powerful serum ever with the highest concentration of ingredients. … Microfluidizer technology is finely absorbed into the skin for bright, radiant skin.”
Also:
“Every product within our RADIANSOME100 series is crafted with microfluidized nano-liposomes, guaranteeing optimal absorption of our exclusive patented natural ingredients and vitamin complexes.”
This matters because for hyperpigmentation and scar marks, getting those actives deep into the skin for ongoing repair (not just surface brightening) can make a difference.

• Holistic target: brightening + repair

The RADIANSOME100 line isn’t just about brightening superficial spots—Incellderm describes its philosophy as:

“The line’s philosophy centers on enhancing the skin's natural luminosity rather than simply masking imperfections. It aims to improve skin clarity, even out skin tone, and promote a healthy, youthful glow.”
For acne scars + hyperpigmentation, you often need more than “just brightening”; you need regeneration, texture improvement, barrier support. This ampoule aims to do that.

• Texture & user experience

The product descriptor:

“Restores, corrects and regenerates skin, yet has a light, smooth texture for easy absorption.”
Since consistent use is key for hyperpigmentation, a formula you want to apply day after day matters.

• Credible positioning in the K-beauty market

The RADIANSOME100 line is recognised and features in Korean skincare discussions as a premium innovation. For example, Incellderm blog posts highlight the difference between their “EX” line vs “RADIANSOME100” and emphasise that the latter prioritises radiance, barrier, tone correction, not just anti-aging.

In short: If you want a “top performance” Korean ampoule for scars + pigmentation, RADIANSOME100 Microfluidizer Ampoule leads.

How to use it (and maximize results)

To get the best outcome with this ampoule (and any targeted scar/pigmentation formula), follow these tips:

  1. Cleanse + tone to prep the skin so actives absorb.
  2. Apply the ampoule (a few drops) after toner, before your heavier moisturizer or crema.
  3. Use spare nights and consistently—marks fade gradually, not overnight.
  4. Always apply sunscreen (SPF) during the day. Without sun protection, pigment-marks will linger and new ones will form.
  5. Layer wisely: If you use exfoliating acids (AHA/BHA) or retinoids, alternate or space out so the skin doesn’t get overloaded. Pair the ampoule with gentle barrier-repair ingredients if you’re using active actives.
  6. Be patient—for hyperpigmentation, expect weeks to months. For texture (scarring), regeneration takes time.

Final thoughts

If you have acne scars and hyperpigmentation and you’re shopping for a Korean ampoule to help you achieve smoother, more even skin tone, you absolutely have strong options with brands like SKIN1004, COSRX, and Beauty of Joseon. However, when I compare ingredient delivery technology, formulation ambition and results-oriented positioning, the Incellderm RADIANSOME100 Microfluidizer Ampoule stands out as the best overall choice.

By investing in a high-quality, research-backed ampoule and combining it with a consistent skincare routine + sun protection, you give your skin the best chance to visibly improve.